Desmin antibody (AA 261-360)

Catalog No. ABIN736566

Product Details anti-Desmin Antibody

Target: Desmin (DES)

Binding Specificity: AA 261-360

Reactivity: Human, Mouse, Rat, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Chicken, Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Desmin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Desmin antibody (ABIN736566)

Li, Xiong, Gong: "Lyn kinase enhanced hepatic fibrosis by modulating the activation of hepatic stellate cells." in: American journal of translational research, Vol. 9, Issue 6, pp. 2865-2877, (2017) (PubMed).

Ersel, Uyanikgil, Karbek Akarca, Ozcete, Altunci, Karabey, Cavusoglu, Meral, Yigitturk, Oyku Cetin: "Effects of Silk Sericin on Incision Wound Healing in a Dorsal Skin Flap Wound Healing Rat Model." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 22, pp. 1064-78, (2016) (PubMed).

Ruan, Zhu, Yin, Chen: "Inhibitor of p53-p21 pathway induces the differentiation of human umbilical cord derived mesenchymal stem cells into cardiomyogenic cells." in: Cytotechnology, Vol. 68, Issue 4, pp. 1257-65, (2016) (PubMed).

Liu, Nelson, Cromeens, Rager, Lannutti, Johnson, Besner: "HB-EGF embedded in PGA/PLLA scaffolds via subcritical CO2 augments the production of tissue engineered intestine." in: Biomaterials, Vol. 103, pp. 150-9, (2016) (PubMed).

Liu, Rager, Johnson, Enmark, Besner: "Enriched Intestinal Stem Cell Seeding Improves the Architecture of Tissue Engineered Intestine." in: Tissue engineering. Part C, Methods, (2015) (PubMed).

Luo, Wu, Ye, Li, Hao, Kong, Zheng, Lin, Nie, Zhang: "The transient expression of miR-203 and its inhibiting effects on skeletal muscle cell proliferation and differentiation." in: Cell death & disease, Vol. 5, pp. e1347, (2014) (PubMed).

Target Details for Desmin

Target: Desmin (DES)

Alternative Name: Desmin (DES Products)

Background:

Synonyms: CSM1, CSM2, LGMD2R, Desmin, DES

Background: Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.

Gene ID: 1674

UniProt: P17661