SEMA3F antibody (AA 651-754) (Biotin)

Catalog No. ABIN737978

Product Details anti-SEMA3F Antibody (Biotin)

Target: SEMA3F (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3F (SEMA3F))

Binding Specificity: AA 651-754

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEMA3F antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Sema3F

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SEMA3F

Target: SEMA3F (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3F (SEMA3F))

Alternative Name: Sema3F/semaphorin 3F (SEMA3F Products)

Synonyms: Sema4 antibody, Semak antibody, SemaIV antibody, semaphorin-3F antibody, sema4 antibody, semak antibody, sema-iv antibody, SEMA3F antibody, SEMA-IV antibody, SEMA4 antibody, SEMAK antibody, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F antibody, semaphorin 3F antibody, semaphorin 3F L homeolog antibody, Sema3f antibody, SEMA3F antibody, sema3f antibody, sema3f.L antibody

Background:

Synonyms: SEMA4, SEMAK, SEMA-IV, Semaphorin-3F, Sema III/F, Semaphorin IV, Sema IV, SEMA3F

Background: The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues(Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A, MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.

Gene ID: 6405

UniProt: Q13275

Pathways: Regulation of Cell Size