Fibrillin 1 antibody (AA 401-500)

Catalog No. ABIN738501

Product Details anti-Fibrillin 1 Antibody

Target: Fibrillin 1 (FBN1)

Binding Specificity: AA 401-500

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrillin 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FBN1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Fibrillin 1

Target: Fibrillin 1 (FBN1)

Alternative Name: Fibrillin 1 (FBN1 Products)

Background:

Synonyms: FBN, SGS, WMS, MASS, MFS1, OCTD, SSKS, WMS2, ACMICD, ECTOL1, GPHYSD2, Fibrillin-1, FBN1

Background: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.

Gene ID: 2200

UniProt: P35555

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome