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GPC1 antibody (AA 301-400) (Cy5.5)

GPC1 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Cy5.5
Catalog No. ABIN740105
  • Target See all GPC1 Antibodies
    GPC1 (Glypican 1 (GPC1))
    Binding Specificity
    • 15
    • 14
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    Reactivity
    • 45
    • 19
    • 14
    Human
    Host
    • 57
    • 8
    • 2
    Rabbit
    Clonality
    • 59
    • 8
    Polyclonal
    Conjugate
    • 27
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This GPC1 antibody is conjugated to Cy5.5
    Application
    • 32
    • 25
    • 25
    • 24
    • 14
    • 8
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human glypican 1
    Isotype
    IgG
    Top Product
    Discover our top product GPC1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    GPC1 (Glypican 1 (GPC1))
    Alternative Name
    Glypican 1 (GPC1 Products)
    Synonyms
    gpc1 antibody, zgc:63947 antibody, GPC1 antibody, Glypican-1 antibody, glypican antibody, AI462976 antibody, HSPG M12 antibody, HSPGM12 antibody, glypican 1b antibody, glypican 1 antibody, gpc1b antibody, GPC1 antibody, gpc1 antibody, Gpc1 antibody
    Background

    Synonyms: glypican, Glypican-1, GPC1

    Background: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

    Gene ID
    2817
    UniProt
    P35052
    Pathways
    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
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