Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) antibody

Details for Product No. ABIN740355, Supplier: Log in to see
Antigen
  • CYP21
  • 21-OH
  • 21OH
  • 21OHA
  • 21OHB
  • CYP21OH-A
  • Cyp21
  • Cyp21-ps1
  • Cyp21B
  • Cyp21a2-ps
  • Cyp21a2ps
  • Oh21-1
  • Oh21-2
  • CA21H
  • CAH1
  • CPS1
  • CYP21B
  • P450c21B
  • CYP21A
  • 21-OHase
  • cytochrome P450, family 21, subfamily A, polypepide 2
  • cytochrome P450, family 21, subfamily a, polypeptide 1
  • cytochrome P450, family 21, subfamily A, polypeptide 2
  • cytochrome P450, subfamily XXI (steroid 21-hydroxylase)
  • cytochrome P450c21
  • steroid 21-hydroxylase-like
  • CYP21A2
  • Cyp21a1
  • CYP21
  • LOC101094596
Alternatives
anti-Human Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 antibody for ELISA
Reactivity
Human, Mouse (Murine), Rat (Rattus)
70
18
18
1
1
1
1
1
Host
Rabbit
74
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
58
33
15
12
12
8
6
4
3
1
1
Options
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Immunogen KLH conjugated synthetic peptide derived from human CYP21
Isotype IgG
Purification Purified by Protein A.
Alternative Name Cyp21 (CYP21A2 Antibody Abstract)
Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene, gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Subcellular location: Membrane bound, Cell membrane

Synonyms: Cytochrome P450 21, cytochrome P450, family 21, subfamily A, polypeptide 2, 21-OH, 21OHA, 21OHB, CA21H, CAH1, CHOLESTEROL 21-HYDROXYLASE, CPS1, CYP21, Cyp21-ps1, Cyp21a1, CYP21A2, Cyp21a2-ps, CYP21B, CYP21OH-A, MGC150536, MGC150537, MGC156449, Oh21-1, Oh21-2, P450C21, P450c21B, CYP21A2, CP21A_HUMAN.

Gene ID 1589
Pathways Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) antibody (ABIN740355) Formalin-fixed and paraffin embedded rat testis labeled with Anti-CYP21 Polyclonal An...
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