Kallikrein 10 antibody (AA 65-165)

Catalog No. ABIN741630

Product Details anti-Kallikrein 10 Antibody

Target: Kallikrein 10 (KLK10)

Binding Specificity: AA 65-165

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NES1/KLK10

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Kallikrein 10 antibody (ABIN741630)

Shimura, Ebi, Yamada, Yamada, Katano, Nojiri, Iwasaki, Nomura, Hayashi, Mori, Kataoka, Moses, Joh: "Urinary kallikrein 10 predicts the incurability of gastric cancer." in: Oncotarget, Vol. 8, Issue 17, pp. 29247-29257, (2018) (PubMed).

Li, Xu, Fan, Meng, Luo, Lv, Ma, Liu, Liu, Xu, Wang, Mao, Li: "Upregulated KLK10 inhibits esophageal cancer proliferation and enhances cisplatin sensitivity in vitro." in: Oncology reports, Vol. 34, Issue 5, pp. 2325-32, (2015) (PubMed).

Wang, Schwab, Fan, Seagroves, Buolamwini: "Chemoprevention Activity of Dipyridamole in the MMTV-PyMT Transgenic Mouse Model of Breast Cancer." in: Cancer prevention research (Philadelphia, Pa.), Vol. 6, Issue 5, pp. 437-47, (2013) (PubMed).

Target Details for Kallikrein 10

Target: Kallikrein 10 (KLK10)

Alternative Name: NES1/KLK10 (KLK10 Products)

Synonyms: KLK10 antibody, 2300002A13Rik antibody, NES1 antibody, PRSSL1 antibody, kallikrein related peptidase 10 antibody, kallikrein related-peptidase 10 antibody, kallikrein-related peptidase 10 antibody, KLK10 antibody, Klk10 antibody

Background:

Synonyms: NES1, PRSSL1, Kallikrein-10, Normal epithelial cell-specific 1, Protease serine-like 1, KLK10

Background: Has a tumor-suppressor role for NES1 in breast and prostate cancer.

Gene ID: 5655

UniProt: O43240

Pathways: Complement System