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TRIM63 antibody (AA 251-353)

TRIM63 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN741750
  • Target See all TRIM63 Antibodies
    TRIM63 (Tripartite Motif Containing 63 (TRIM63))
    Binding Specificity
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-353
    Reactivity
    • 46
    • 25
    • 23
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 30
    • 15
    • 1
    • 1
    Rabbit
    Clonality
    • 35
    • 12
    Polyclonal
    Conjugate
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIM63 antibody is un-conjugated
    Application
    • 36
    • 15
    • 14
    • 12
    • 12
    • 10
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MuRF1/Trim63
    Isotype
    IgG
    Top Product
    Discover our top product TRIM63 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Lu, Wang, Xie, Zhang, Sun: "Tumor necrosis factor-like weak inducer of apoptosis regulates quadriceps muscle atrophy and fiber-type alteration in a rat model of chronic obstructive pulmonary disease." in: Tobacco induced diseases, Vol. 15, pp. 43, (2017) (PubMed).

    Lin, Hanson, Betik, Brennan-Speranza, Hayes, Levinger: "Hindlimb Immobilization, But Not Castration, Induces Reduction of Undercarboxylated Osteocalcin Associated With Muscle Atrophy in Rats." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 11, pp. 1967-1978, (2016) (PubMed).

  • Target
    TRIM63 (Tripartite Motif Containing 63 (TRIM63))
    Alternative Name
    MuRF1/Trim63 (TRIM63 Products)
    Synonyms
    IRF antibody, MURF1 antibody, MURF2 antibody, RNF28 antibody, SMRZ antibody, Murf antibody, Murf1 antibody, Rnf28 antibody, MuRF1 antibody, RF1 antibody, rnf30 antibody, MGC80210 antibody, TRIM63 antibody, MuRF antibody, fc50c07 antibody, trim63 antibody, wu:fc50c07 antibody, zgc:86757 antibody, tripartite motif containing 63 antibody, tripartite motif-containing 63 antibody, tripartite motif containing 63 S homeolog antibody, tripartite motif containing 63a antibody, TRIM63 antibody, Trim63 antibody, trim63.S antibody, trim63a antibody
    Background

    Synonyms: MuRF 1, MuRF-1, Muscle-specic RING finger protein 1, Muscle-specic RING finger protein 1, E3 ubiquitin-protein ligase TRIM63, FLJ32380, IRF, MURF1, MURF 1, MURF2, RNF28, SMRZ, Iris ring finger protein, Muscle specic ring finger protein 2, Ring finger protein 28, RNF28, SMRZ, Striated muscle RING zinc finger protein, TRIM 63, TRIM63, Tripartite mot containing 63, Tripartite mot containing protein 63, Ubiquitin ligase TRIM63.

    Background: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq].

    Gene ID
    84676
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