IL22RA2 antibody (AA 165-263)

Catalog No. ABIN748193

Product Details anti-IL22RA2 Antibody

Target: IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))

Binding Specificity: AA 165-263

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL22RA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL22RA2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IL22RA2

Target: IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))

Alternative Name: IL22RA2 (IL22RA2 Products)

Synonyms: CRF2-10 antibody, CRF2-S1 antibody, CRF2X antibody, IL-22BP antibody, IL-22R-alpha-2 antibody, IL-22RA2 antibody, ZCYTOR16 antibody, CRF2-s1 antibody, Il-22bp antibody, Crf2-s1 antibody, interleukin 22 receptor subunit alpha 2 antibody, interleukin 22 receptor, alpha 2 antibody, IL22RA2 antibody, Il22ra2 antibody

Background:

Synonyms: Interleukin-22 receptor subunit alpha-2, IL-22 receptor subunit alpha-2, IL-22R-alpha-2, IL-22RA2, Cytokine receptor class-II member 10, Cytokine receptor family 2 member 10, CRF2-10, Cytokine receptor family type 2, soluble 1, CRF2-S1, Interleukin-22-binding protein, IL-22BP, IL22BP, ZcytoR16, IL22RA2, UNQ5793/PRO19598/PRO19822

Background: IL22RA2 is a member of the class II cytokine receptor family. The soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. IL22RA2 may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Isoform 2 is a receptor for IL22, and may play an important role as an IL22 antagonist in the regulation of inflammatory responses. Isoform 1 may play a role in establishing and maintaining a successful pregnancy.

Gene ID: 116379

UniProt: Q969J5