Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

LAG3 antibody (AA 210-260) (PE)

LAG3 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal PE
Catalog No. ABIN748518
  • Target See all LAG3 Antibodies
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Binding Specificity
    • 15
    • 14
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 210-260
    Reactivity
    • 87
    • 33
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 51
    • 35
    • 7
    • 4
    Rabbit
    Clonality
    • 52
    • 42
    • 1
    Polyclonal
    Conjugate
    • 52
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LAG3 antibody is conjugated to PE
    Application
    • 68
    • 36
    • 30
    • 29
    • 25
    • 22
    • 15
    • 13
    • 13
    • 10
    • 10
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3
    Isotype
    IgG
    Top Product
    Discover our top product LAG3 Primary Antibody
  • Application Notes
    FCM(1:20-100)
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Parodi, Battaglia, Kalli, Ferrera, Conteduca, Tardito, Stringara, Ivaldi, Negrini, Borgonovo, Simonato, Traverso, Carmignani, Fenoglio, Filaci: "CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes." in: Cancer immunology, immunotherapy : CII, Vol. 62, Issue 5, pp. 851-62, (2013) (PubMed).

  • Target
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Alternative Name
    Lymphocyte Activation Gene 3 (LAG3 Products)
    Synonyms
    CD223 antibody, LAG-3 antibody, Ly66 antibody, lymphocyte activating 3 antibody, lymphocyte-activation gene 3 antibody, LAG3 antibody, Lag3 antibody
    Background

    Synonyms: CD223, Lymphocyte activation gene 3 protein, LAG-3, Lag3

    Background: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.

    Gene ID
    297596
    UniProt
    Q5BK54
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
You are here:
Support