GNB2 antibody (AA 121-220) (HRP)

Catalog No. ABIN751492

Product Details anti-GNB2 Antibody (HRP)

Target: GNB2 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2 (GNB2))

Binding Specificity: AA 121-220

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNB2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein beta 2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GNB2

Target: GNB2 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2 (GNB2))

Alternative Name: G protein beta 2/GNB2 (GNB2 Products)

Synonyms: XGB1 antibody, XGbeta1 antibody, gnb2 antibody, Gnb-2 antibody, im:7138539 antibody, zgc:113357 antibody, guanine nucleotide binding protein (G protein), beta polypeptide 1 antibody, G protein subunit beta 2 antibody, guanine nucleotide binding protein (G protein), beta 2 antibody, guanine nucleotide binding protein (G protein), beta polypeptide 2 antibody, gnb1 antibody, GNB2 antibody, Gnb2 antibody, gnb2 antibody

Background:

Synonyms: G protein beta 2 subunit, G protein subunit beta 2, G protein, beta 2 subunit, Gnb2l1, guanine nucleotide binding protein G protein, beta polypeptide 2, Guanine nucleotide binding protein beta 2 subunit, Guanine nucleotide binding protein G I G S G T beta 2 subunit 2, Guanine nucleotide binding protein G protein beta polypeptide 2, guanine nucleotide binding protein, beta 2 subunit, RACK1, Receptor for activated C kinase, Receptor of activated protein kinase C 1, signal transducing guanine nucleotide binding regulatory protein beta, Transducin beta chain 2, OTTHUMP00000174601, OTTHUMP00000174602, GBB2_HUMAN.

Background: GNB2 belongs to the WD repeat G protein beta family. Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Gene ID: 2783

Pathways: Myometrial Relaxation and Contraction