CD131 antibody (pTyr766)

Catalog No. ABIN757087

Product Details anti-CD131 Antibody

Target: CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))

Binding Specificity: pTyr766

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD131 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Predicted Reactivity: Human,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human CSF2RB around the phosphorylation site of Tyr766

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CD131

Target: CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))

Alternative Name: CSF2RB (CSF2RB Products)

Synonyms: Csf2rb1 antibody, CSF2RB antibody, cd131 antibody, cdw131 antibody, il3rb antibody, il5rb antibody, il-3rbc antibody, CD131 antibody, CDw131 antibody, IL3RB antibody, IL5RB antibody, SMDP5 antibody, AI848964 antibody, AIC2B antibody, Bc antibody, Csfgmrb antibody, Il3r antibody, Il3rb antibody, Il3rb1 antibody, Il5rb antibody, colony stimulating factor 2 receptor beta common subunit antibody, colony stimulating factor 2 receptor beta common subunit S homeolog antibody, cytokine receptor common subunit beta-like antibody, colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) antibody, CSF2RB antibody, Csf2rb antibody, csf2rb.S antibody, CRCBL antibody, csf2rb antibody

Background:

Synonyms: GM-CSF receptor beta chain, Cytokine receptor common subunit beta, CDw131, GM-CSF/IL-3/IL-5 receptor common beta subunit, CSF2RB, IL3RB, IL5RB: GM-CSFr_.

Background: GM-CSF Receptor Beta is the v subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Six transcript variants encoding five different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.

Gene ID: 1439

Pathways: JAK-STAT Signaling