Periostin, Osteoblast Specific Factor (POSTN) antibody

Antigen: Periostin, Osteoblast Specific Factor (POSTN)

Synonyms: PN, OSF2, OSF-2, PDLPOSTN, MGC119510, MGC119511, periostin, RP11-412K4.1, PLF, Osf2, peri, AI747096, Periostin, MGC128214, pn, fa99h07, MGC153873, wu:fa99h07, wu:fc70f09, zgc:153873, LOC100008945, osf-2, pdlpostn

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rabbit, Rat (Rattus), Mouse (Murine), Pig (Porcine), Horse (Equine), Cow (Bovine)

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunofluorescence (IF)

Catalog no.: ABIN759416

Additional Information

Alternative name: Periostin

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human Periostin.

Format: Lyophilized

Reconstitution: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotype: IgG  (Matching secondary antibodies)

Description: Synonym: OSF 2, OSF2, osteoblast specific factor 2 (fasciclin I-like), Osteoblast specific factor 2, Osteoblast specific factor, PDLPOSTN, Periodontal ligament specific periostin, Periostin isoform thy2, Periostin isoform thy4, Periostin isoform thy6, Periostin isoform thy8, Periostin osteoblast specific factor, PN, POSTN.

Molecular Weight: 100kDa

Comments:

Periostin is a disulfide linked 90 kDa

811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment

attachment and spreading. Additionally

periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1(TGF beta 1) and bone morphogenetic protein (BMP2). Periostin has a typical signal sequence

followed by a cysteine-rich domain

a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF2 shows homology with the insect protein fasciclin. Periostin mRNA is expressed in the developing mouse embryonic and fetal heart

and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors.

Synonyms: PN, OSF2, OSF-2, PDLPOSTN, MGC119510, MGC119511, periostin, RP11-412K4.1, PLF, Osf2, peri, AI747096, Periostin, MGC128214, pn, fa99h07, MGC153873, wu:fa99h07, wu:fc70f09, zgc:153873, LOC100008945, osf-2, pdlpostn

Application Details

Application Notes: WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)

Concentration: 1mg/1ml

Purification: affinity purified by Protein A

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Storage: Ship at room temperature. Store at -20°C

Research Area: Cardiovascular, Cardiogenesis, Atherosclerosis, Extracellular Matrix

Restrictions: For Research Use only