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+1 404 474 4654 |
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+1 888 205 9894 (TF) |
HIF3 alpha antibody (RBITC)
| Antigen | HIF3 alpha |
| Clonality | Polyclonal |
| Host |
Alternatives Rabbit |
| Reactivity |
Alternatives Human, Mouse (Murine) |
| Conjugate |
Alternatives RBITC |
| Application |
Alternatives Flow Cytometry (FACS), Immunofluorescence (IF)
|
| Catalog no. | ABIN759520 |
| Quantity | 100 µg (1mg/1ml) |
| Price | 290.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 10 to 15 Business Days |
Additional Information
| Immunogen | Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human HIF3 alpha |
| Format | Lyophilized |
| Reconstitution | Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%) |
| Isotype | IgG |
| Description | Synonym: HIF 3 alpha, HIF-3 Alpha, HIF 3A, HIF 3A4, HIF3 alpha, HIF3A, HIF 3A, HIF-3A, Hypoxia Inducible Factor 3 alpha, Hypoxia inducible factor 3 alpha subunit, Hypoxia inducible factor three alpha, Inhibitory PAS domain protein, IPAS, MOP7, PASD7. |
| Specificity | Excitation / Emission Wavelengths: 495nm/519nm |
| Molecular Weight | 60-72kDa |
| Comments |
Hypoxia-inducible factor (HIF) is one of the most important factors in the cellular response to hypoxia transcriptionally activating genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three subunits HIF1 alpha HIF2 alpha or HIF3 alpha. HIF target genes play critical roles in metabolism angiogenesis cell proliferation and cell survival. HIF3 alpha protein is one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. HIF3 alpha may be a marker for tumor growth and angiogenesis. |
Application Details
| Application Notes | Flow-Cyt (1:50-200), IF (1:50-200) |
| Concentration | 1mg/1ml |
| Purification | Antibodies are purified by protein A and peptide affinity chromatography. |
| Buffer | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| Storage | Ship at room temperature. Store at -20°C |
| Research Area | Cancer, Transcription Factors |
| Restrictions | For Research Use only |
Alternatives
| Hosts | Rabbit (19) |
| Reactivities | Human (19), Mouse (Murine) (18), Rat (Rattus) (4), Horse (Equine) (3), Cow (Bovine) (2), Dog (Canine) (2), Pig (Porcine) (2), Chicken (1), Rabbit (1) |
| Applications | Flow Cytometry (FACS) (17), Immunofluorescence (IF) (17), ELISA (3), Western Blotting (WB) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1) |
| Conjugates | Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1) |




Alternatives