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HIF3 alpha antibody (RBITC)

Antigen

HIF3 alpha

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human, Mouse (Murine)

Conjugate
Alternatives RBITC
Application
Alternatives Flow Cytometry (FACS), Immunofluorescence (IF)
Catalog no. ABIN759520
Quantity 100 µg  (1mg/1ml)
Price 290.00 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 10 to 15 Business Days

Additional Information

Immunogen Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human HIF3 alpha
Format Lyophilized
Reconstitution Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
Isotype IgG
Description Synonym: HIF 3 alpha, HIF-3 Alpha, HIF 3A, HIF 3A4, HIF3 alpha, HIF3A, HIF 3A, HIF-3A, Hypoxia Inducible Factor 3 alpha, Hypoxia inducible factor 3 alpha subunit, Hypoxia inducible factor three alpha, Inhibitory PAS domain protein, IPAS, MOP7, PASD7.
Specificity Excitation / Emission Wavelengths: 495nm/519nm
Molecular Weight 60-72kDa
Comments

Hypoxia-inducible factor (HIF) is one of the most important factors in the cellular response to hypoxia

transcriptionally activating genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three subunits

HIF1 alpha

HIF2 alpha

or HIF3 alpha. HIF target genes play critical roles in metabolism

angiogenesis

cell proliferation and cell survival. HIF3 alpha protein is one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. HIF3 alpha may be a marker for tumor growth and angiogenesis.

Application Details

Application Notes Flow-Cyt (1:50-200), IF (1:50-200)
Concentration 1mg/1ml
Purification Antibodies are purified by protein A and peptide affinity chromatography.
Buffer 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
Storage Ship at room temperature. Store at -20°C
Research Area Cancer, Transcription Factors
Restrictions For Research Use only

Alternatives

Alternatives for antigen "HIF3 alpha", type "Antibodies"
Hosts Rabbit (19)
Reactivities Human (19), Mouse (Murine) (18), Rat (Rattus) (4), Horse (Equine) (3), Cow (Bovine) (2), Dog (Canine) (2), Pig (Porcine) (2), Chicken (1), Rabbit (1)
Applications Flow Cytometry (FACS) (17), Immunofluorescence (IF) (17), ELISA (3), Western Blotting (WB) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)