Desmoglein 1 antibody (AA 841-855)

Catalog No. ABIN769050

Product Details anti-Desmoglein 1 Antibody

Target: Desmoglein 1 (DSG1)

Binding Specificity: AA 841-855

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Desmoglein 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human DSG1.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gibbon (100%) Gorilla, Monkey, Marmoset, Panda (93%) Mouse, Rat, Dog, Rabbit, Horse, Pig (87%) Elephant, Bat, Bovine (80%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-YTTSDTLKPSVHVHD from an internal region of human DSG1 (NP_001933.2). Percent identity by BLAST analysis: Human, Gibbon (100%), Gorilla, Monkey, Marmoset, Panda (93%), Mouse, Rat, Dog, Rabbit, Horse, Pig (87%), Elephant, Bat, Bovine (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:32000)

Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments in lysates of cell lines A431, HeLa, K562 and MOLT4 gave no specific signal but low background (at antibody concentration up to 1 μg/mL).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Desmoglein 1

Target: Desmoglein 1 (DSG1)

Alternative Name: DSG1 / Desmoglein 1 (DSG1 Products)

Synonyms: CDHF4 antibody, DG1 antibody, DSG antibody, PPKS1 antibody, SPPK1 antibody, DSG-1 antibody, DSG1 antibody, Dsg1b antibody, Dsg1c antibody, desmoglein 1 antibody, desmoglein 4 antibody, DSG1 antibody, DSG4 antibody, Dsg1 antibody

Background: Name/Gene ID: DSG1
Family: Cadherin

Synonyms: DSG1, CDHF4, Cadherin family member 4, Desmoglein 1, DG1, Desmoglein-1, Desmosomal glycoprotein 1, SPPK1, DGI, DSG, Pemphigus foliaceus antigen, PPKS1

Gene ID: 1828

NCBI Accession: NP_001933

UniProt: Q02413

Pathways: Cell-Cell Junction Organization