Leptin Receptor antibody

Catalog No. ABIN781204

Product Details anti-Leptin Receptor Antibody

Target: Leptin Receptor (LEPR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Leptin Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Plasma membrane

Purification: Protein G-Sepharose affinity purified.

Immunogen: Recombinant fragment of Human LEPR (N-terminus).

Isotype: IgG

Application Details

Application Notes: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1% BSA ,PBS, pH7.4.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Leptin Receptor

Target: Leptin Receptor (LEPR)

Alternative Name: LEPR (LEPR Products)

Synonyms: CD295 antibody, LEP-R antibody, LEPRD antibody, OB-R antibody, OBR antibody, obr antibody, cd295 antibody, ob-rb antibody, Fa antibody, LEPROT antibody, Leprb antibody, Modb1 antibody, OB-RGRP antibody, Obr antibody, db antibody, diabetes antibody, obese-like antibody, obl antibody, ObRb antibody, Ob-R antibody, Ob-RM antibody, lepr antibody, leptin receptor antibody, leptin receptor S homeolog antibody, LEPR antibody, lepr antibody, Lepr antibody, lepr.S antibody

Background: Leptin receptor (LEPR, OB-R) is a type I cytokine receptor family protein with significant amino acid sequence identity with gp130, G-CSF receptor, and LIF receptor. The transcript was reported to be expressed predominantly in regions of the hypothalamus previously thought to be important in body weight regulation. OB-R binds leptin with high affinity and is a potent leptin antagonist.

Molecular Weight: 120kDa

NCBI Accession: NM_002303

Pathways: JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour