NPR2 antibody

Catalog No. ABIN781940

Product Details anti-NPR2 Antibody

Target: NPR2 (Natriuretic Peptide Receptor B/guanylate Cyclase B (Atrionatriuretic Peptide Receptor B) (NPR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NPR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to NPR2.

Purification: Affinity chromatography on Protein A

Immunogen: NPR2 antibody was raised against recombinant protein

Clone: 2A6

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0,22 mg/mL

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NPR2

Target: NPR2 (Natriuretic Peptide Receptor B/guanylate Cyclase B (Atrionatriuretic Peptide Receptor B) (NPR2))

Alternative Name: NPR2 / ANPRB (NPR2 Products)

Synonyms: NPR2 antibody, GC-B antibody, GC-B2 antibody, GC-B3 antibody, cn antibody, mNPR-B antibody, pwe antibody, AMDM antibody, ANPRB antibody, ANPb antibody, GUC2B antibody, GUCY2B antibody, NPRB antibody, NPRBi antibody, NPR-B antibody, natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) antibody, natriuretic peptide receptor 2 antibody, NPR2 antibody, Npr2 antibody

Background: NPR2 encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, an intracellularly a protein kinase homology domain, an helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. NPR2 is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity.Synonyms: ANP receptor B, ANP-B, Atrial natriuretic peptide B-type receptor, GC-B, Guanylate cyclase B, NPR-B

Gene ID: 4882

NCBI Accession: NP_003986

UniProt: P20594