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Aurora A antibody (Aurora Kinase A) (C-Term)

Details for Product anti-AURKA Antibody No. ABIN782867, Supplier: Login to see New
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Antigen
Synonyms
87A7-9/2, Aur-A, AurA, CG3068, Dmel\\CG3068, aur-A, aurA, ck10, ck[10], l(3)87Ac, l(3)ck10, Aurora-A, Eg2, aik, ark1, aur-a, aura, aurora2, btak, pEg2, stk15, stk6, stk7, wu:fb37c10, wu:fc02c02, zgc:1 ... show more
87A7-9/2, Aur-A, AurA, CG3068, Dmel\\CG3068, aur-A, aurA, ck10, ck[10], l(3)87Ac, l(3)ck10, Aurora-A, Eg2, aik, ark1, aur-a, aura, aurora2, btak, pEg2, stk15, stk6, stk7, wu:fb37c10, wu:fc02c02, zgc:100912, AURKA, aurka, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7, AIRK1, AU019385, AW539821, Ark1, Ayk1, IAK, IAK1, Stk6, ARK-1, aurka-a show less
Alternatives
Epitope
C-Term
(46), (44), (31), (15), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(226), (76), (49), (14), (8), (8), (3), (2), (1), (1), (1), (1)
Host
Goat
(177), (57), (19)
Clonality
Polyclonal
Conjugate
This Aurora A antibody is un-conjugated
(12), (6), (6), (5), (5), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(192), (88), (77), (55), (39), (32), (19), (16), (12), (5), (4), (2), (1), (1)
Pubmed 1 reference available
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Quantity 20 μg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide from the C Terminus of the protein sequence according to NP_003591.2.
Sequence C-QNKESASKQS
Specificity This antibody detects Aurora kinase A / AURKA at C-term.
Purification Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
Alternative Name Aurora Kinase A (AURKA Antibody Abstract)
Background Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Synonyms: AIK1, ARK1, AURA, AURKA, AURORA2, Aurora/IPL1-related kinase 1, BTAK, Breast tumor-amplified kinase, STK15, STK6, Serine/threonine kinase 15, Serine/threonine-protein kinase 6
Gene ID 6790
NCBI Accession NP_003591
UniProt O14965
Pathways Cell Division Cycle
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Aurora A antibody (Aurora Kinase A) (C-Term) (ABIN782867) anti-Aurora Kinase A (AURKA) (C-Term) antibody
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Background publications Zhou, Kuang, Zhong et al.: "Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation." in: Nature genetics, Vol. 20, Issue 2, pp. 189-93, 1998 (PubMed).

Catalog No. ABIN782867
$203.50
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