Aurora Kinase A (AURKA) (C-Term) antibody

Details for Product No. ABIN782867
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Antigen
Synonyms
87A7-9/2, Aur-A, AurA, CG3068, Dmel\\CG3068, aur-A, aurA, ck10, ck[10], l(3)87Ac, l(3)ck10, Aurora-A, Eg2, aik, ark1, aur-a, aura, aurora2, btak, pEg2, stk15, stk6, stk7, wu:fb37c10, wu:fc02c02, zgc:1 ... show more
87A7-9/2, Aur-A, AurA, CG3068, Dmel\\CG3068, aur-A, aurA, ck10, ck[10], l(3)87Ac, l(3)ck10, Aurora-A, Eg2, aik, ark1, aur-a, aura, aurora2, btak, pEg2, stk15, stk6, stk7, wu:fb37c10, wu:fc02c02, zgc:100912, AURKA, aurka, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7, AIRK1, AU019385, AW539821, Ark1, Ayk1, IAK, IAK1, Stk6, ARK-1, aurka-a show less
Epitope
C-Term
(29), (25), (14), (7), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(169), (58), (49), (28), (26), (13), (13)
Host
Goat
(128), (44), (10), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(135), (72), (45), (39), (35), (27), (20), (20), (9), (5), (1), (1)
Pubmed 1 reference available
Quantity 20 µg
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Catalog No. ABIN782867
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Immunogen Peptide from the C Terminus of the protein sequence according to NP_003591.2.
Sequence C-QNKESASKQS
Specificity This antibody detects Aurora kinase A / AURKA at C-term.
Purification Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
Alternative Name Aurora kinase A
Background Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
Alternate names: AIK1, ARK1, AURA, AURKA, AURORA2, Aurora/IPL1-related kinase 1, BTAK, Breast tumor- amplified kinase, STK15, STK6, Serine/threonine kinase 15, Serine/threonine-protein kinase 6
Gene ID 6790
NCBI Accession NP_003591
UniProt O14965
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Supplier Images
anti-Aurora Kinase A (AURKA) (C-Term) antibody anti-Aurora Kinase A (AURKA) (C-Term) antibody
anti-Aurora Kinase A (AURKA) (C-Term) antibody (2) anti-Aurora Kinase A (AURKA) (C-Term) antibody (Image 2)
Background publications Zhou, Kuang, Zhong et al.: "Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation." in: Nature genetics, Vol. 20, Issue 2, pp. 189-93, 1998 (PubMed).

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