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Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (Internal Region) antibody

Details for Product No. ABIN782967
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Antigen
Synonyms KLRK1, NKG2D, CD314, D12S2489E, KLR, NKG2-D, D6H12S2489E, Nkg2d, Nkrp2
Epitope
Internal Region
(8), (4), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(94), (80), (19)
Host
Goat
(44), (43), (35), (30), (7), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(18), (16), (13), (8), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(132), (27), (24), (24), (14), (12), (11), (6), (3), (2), (2), (1)
Pubmed 1 reference available
Quantity 20 µg
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Catalog No. ABIN782967
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Immunogen Peptide with sequence C-KVYSKEDQDLLK, from the internal region of the protein sequence
Specificity This antibody reacts to CD314. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat.
Purification Affinity chromatography
Alternative Name CD314 / KLRK1
Background NKG2D is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. NKG2D forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of NKG2D include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to NKG2D results in NK cell activation and potent costimulation of effector T cells.
Alternate names: D12S2489E, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2D
Gene ID 22914
NCBI Accession 9606
UniProt P26718
Restrictions For Research Use only
Format Liquid
Concentration 0,5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (Internal Region) antibody anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (Internal Region) antibody
Background publications Hayakawa, Smyth: "Innate immune recognition and suppression of tumors." in: Advances in cancer research, Vol. 95, pp. 293-322, 2006 (PubMed).

Validation Images
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