ARNTL antibody (AA 569-573)

Catalog No. ABIN783300

Product Details anti-ARNTL Antibody

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Binding Specificity: AA 569-573

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARNTL antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: S-S-S-I-L

Specificity: This antibody detects endogenous level of total BMAL1 protein.

Cross-Reactivity (Details): Species reactivity (expected):Human, Mouse, Rat

Purification: Affinity-chromatography using epitope-specific peptide

Immunogen: Peptide sequence around aa.569~573 derived from Human BMAL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store (in aliquots) at -20 °C.

Target Details for ARNTL

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Alternative Name: ARNTL / BMAL1 (ARNTL Products)

Synonyms: BMAL1 antibody, BMAL1c antibody, JAP3 antibody, MOP3 antibody, PASD3 antibody, TIC antibody, bHLHe5 antibody, Bmal1 antibody, ARNTL antibody, xBmal1 antibody, arntl antibody, Arnt3 antibody, BMAL1b antibody, bmal1b' antibody, aryl hydrocarbon receptor nuclear translocator like antibody, aryl hydrocarbon receptor nuclear translocator-like antibody, aryl hydrocarbon receptor nuclear translocator like S homeolog antibody, ARNTL antibody, Arntl antibody, arntl.S antibody, arntl antibody

Background: ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins.Synonyms: Aryl hydrocarbon receptor nuclear translocator-like protein 1, BHLHE5, Basic-helix-loop-helix-PAS protein MOP3, Brain and muscle ARNT-like 1, Class E basic helix-loop-helix protein 5, MOP3, Member of PAS protein 3, PAS domain-containing protein 3, PASD3, bHLH-PAS protein JAP3, bHLHe5

Molecular Weight: 69 kDa

Gene ID: 406

NCBI Accession: NP_001025443

UniProt: O00327

Pathways: Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect