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Caspase 3 antibody (AA 29-33)

CASP3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783310
  • Target See all Caspase 3 (CASP3) Antibodies
    Caspase 3 (CASP3)
    Binding Specificity
    • 19
    • 16
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 14
    • 13
    • 12
    • 11
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-33
    Reactivity
    • 279
    • 193
    • 149
    • 31
    • 17
    • 10
    • 10
    • 9
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 280
    • 40
    • 4
    • 2
    • 2
    Rabbit
    Clonality
    • 274
    • 53
    Polyclonal
    Conjugate
    • 159
    • 26
    • 21
    • 14
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    This Caspase 3 antibody is un-conjugated
    Application
    • 252
    • 108
    • 104
    • 85
    • 79
    • 65
    • 52
    • 36
    • 31
    • 29
    • 28
    • 19
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    S-G-I-S-L
    Specificity
    This antibody detects endogenous level of total Caspase 3 protein.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Affinity-chromatography using epitope-specific peptide
    Immunogen
    Peptide sequence around aa.29~33 derived from Caspase 3
    Top Product
    Discover our top product CASP3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store (in aliquots) at -20 °C.
  • Target
    Caspase 3 (CASP3)
    Alternative Name
    Caspase-3 (CASP3 Products)
    Synonyms
    CPP32 antibody, CPP32B antibody, SCA-1 antibody, A830040C14Rik antibody, AC-3 antibody, Apopain antibody, CC3 antibody, Caspase-3 antibody, Lice antibody, Yama antibody, mldy antibody, xcpp32 antibody, casp3 antibody, zgc:100890 antibody, CASP-3 antibody, caspase-3 antibody, caspase 3 antibody, caspase 3 S homeolog antibody, caspase 3, apoptosis-related cysteine peptidase a antibody, caspase 3, apoptosis-related cysteine peptidase antibody, CASP3 antibody, Casp3 antibody, casp3.S antibody, casp3a antibody
    Background
    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.Synonyms: Apopain, CASP-3, CASP3, CPP-32, CPP32, Cysteine protease CPP32, SCA-1, SCA1, SREBP cleavage activity 1, Yama protein
    Molecular Weight
    35/19/17 kDa
    Gene ID
    836
    NCBI Accession
    NP_004337
    UniProt
    P42574
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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