Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN783335

Casein Kinase 2, alpha 1 Polypeptide (CSNK2A1) (AA 353-357) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms CK-II, CSNK2A1, CK2A1, CKII, CSNK2A3, Csnk2a1-rs4, ck2a1, csnk2a1, wu:fi38e04, wu:fi38h03, im:6891713, si:ch211-133n4.5, CK2A, CK2, Ck2a, BmCK2a, Ckiialpha
Epitope
»Alternatives AA 353-357
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN783335
Quantity 50 µL
Price
242.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide sequence around aa. 353~357
Sequence C-S-G-I-S
Specificity This antibody detects endogenous levels of total CK2 protein. Species Reactivity: Tested: Human, Mouse, Rat
Purification Affinity-chromatography using epitope-specific peptide
Alternative Name Casein kinase II subunit alpha
Background Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
Alternate names: CK II alpha, CK2A1, CSNK2A1
Molecular Weight 42 kDa
Gene ID 1457
NCBI Accession NP_001886
UniProt P68400
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Expiry Date 12 months
Background publications Niefind, Guerra, Ermakowa et al.: "Crystallization and preliminary characterization of crystals of human protein kinase CK2." in: Acta crystallographica. Section D, Biological crystallography, Vol. 56, Issue Pt 12, pp. 1680-4, 2001 (PubMed).

Keller, Zeng, Wang et al.: "A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1." in: Molecular cell, Vol. 7, Issue 2, pp. 283-92, 2001 (PubMed).

Keller, Lu: "p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 50206-13, 2002 (PubMed).

Trembley, Tatsumi, Sakashita et al.: "Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation." in: Molecular and cellular biology, Vol. 25, Issue 4, pp. 1446-57, 2005 (PubMed).

Alternatives for antigen "Casein Kinase 2, alpha 1 Polypeptide (CSNK2A1)", type "Antibodies"
Hosts (68), (22)
Reactivities (91), (37), (32), (13), (12), (7), (3), (2), (1), (1), (1), (1)
Applications (81), (35), (19), (17), (14), (10), (3), (3), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Beacon