CXXC5 antibody (N-Term)

Catalog No. ABIN783347

Product Details anti-CXXC5 Antibody

Target: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXXC5 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects CXXC5 at N-term. At least two isoforms of CXXC5 are known to exist. CXXC5 antibody is predicted to not cross-react with other CXXC protein family members.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the amino terminus of human CXXC5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for CXXC5

Target: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Alternative Name: CXXC5 (CXXC5 Products)

Synonyms: 4930415K17Rik antibody, CF5 antibody, RINF antibody, WID antibody, CXXC finger 5 antibody, CXXC finger protein 5 antibody, Cxxc5 antibody, CXXC5 antibody

Background: CXXC5 is zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development. CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitated the response of the stem cells to Wnt3a. Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development.Synonyms: CXXC-type zinc finger protein 5, PM08, Putative MAPK-activating protein PM08, Putative NF-kappa-B-activating protein 102

Gene ID: 51523

NCBI Accession: NP_057547

UniProt: Q7LFL8