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ZBTB5 antibody (C-Term)

ZBTB5 Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783357
  • Target See all ZBTB5 Antibodies
    ZBTB5 (Zinc Finger and BTB Domain Containing 5 (ZBTB5))
    Binding Specificity
    • 15
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 34
    Rabbit
    Clonality
    • 34
    Polyclonal
    Conjugate
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZBTB5 antibody is un-conjugated
    Application
    • 33
    • 16
    • 13
    • 13
    • 13
    • 7
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects ZBTB5 at C-term. At least two isoforms of ZBTB5 are known to exist, this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    16 amino acid peptide near the carboxy terminus of human ZBTB6
    Top Product
    Discover our top product ZBTB5 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    ZBTB5 (Zinc Finger and BTB Domain Containing 5 (ZBTB5))
    Alternative Name
    ZBTB5 (ZBTB5 Products)
    Synonyms
    5930421I10 antibody, 9430083K24Rik antibody, AI646847 antibody, mKIAA0354 antibody, zinc finger and BTB domain containing 5 antibody, ZBTB5 antibody, Zbtb5 antibody
    Background
    The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21. ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter. ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.Synonyms: KIAA0354, Zinc finger and BTB domain-containing protein 5
    Gene ID
    9925
    NCBI Accession
    NP_055687
    UniProt
    O15062
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