ZBTB8A antibody (C-Term)

Catalog No. ABIN783363

Product Details anti-ZBTB8A Antibody

Target: ZBTB8A (Zinc Finger and BTB Domain Containing 8A (ZBTB8A))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB8A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects ZBTB8 at C-term. At least two isoforms of ZBTB8 are known to exist, this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of human ZBTB8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for ZBTB8A

Target: ZBTB8A (Zinc Finger and BTB Domain Containing 8A (ZBTB8A))

Alternative Name: ZBTB8 (ZBTB8A Products)

Synonyms: BOZF1 antibody, ZBTB8 antibody, ZNF916A antibody, 2410081M15Rik antibody, AI480941 antibody, Zbtb8 antibody, zinc finger and BTB domain containing 8A antibody, zinc finger and BTB domain containing 8a antibody, ZBTB8A antibody, Zbtb8a antibody

Background: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.Synonyms: BOZ-F1, ZBTB8A, Zinc finger and BTB domain-containing protein 8

Gene ID: 653121

NCBI Accession: NP_001035531

UniProt: Q96BR9