ZMYM3 antibody (N-Term)

Catalog No. ABIN783369

Product Details anti-ZMYM3 Antibody

Target: ZMYM3 (Zinc Finger Protein 261 (ZMYM3))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZMYM3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects ZMYM3 at N-term. At least three isoforms of ZMYM3 are known to exist, this antibody will detect all three. ZMYM3 antibody is predicted to not cross-react with other ZMYM protein family members.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogen: 20 amino acid peptide near the amino terminus of human AXIN2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for ZMYM3

Target: ZMYM3 (Zinc Finger Protein 261 (ZMYM3))

Alternative Name: ZMYM3 (ZMYM3 Products)

Synonyms: ZNF261 antibody, si:ch211-173p18.2 antibody, DXS6673E antibody, MYM antibody, XFIM antibody, ZNF198L2 antibody, 9030216B10Rik antibody, AW122925 antibody, DXS6673El antibody, Zfp261 antibody, zinc finger MYM-type containing 3 antibody, si:ch211-173p18.3 antibody, zinc finger, MYM-type 3 antibody, ZMYM3 antibody, si:ch211-173p18.3 antibody, Zmym3 antibody

Background: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM3 is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X,13) involving this gene is associated with X-linked mental retardation.Synonyms: DXS6673E, KIAA0385, ZNF261, Zinc finger MYM-type protein 3, Zinc finger protein 261

Gene ID: 9203

NCBI Accession: NP_001164633

UniProt: Q14202