LRRTM1 antibody (C-Term)

Catalog No. ABIN783379

Product Details anti-LRRTM1 Antibody

Target: LRRTM1 (Leucine Rich Repeat Transmembrane Neuronal 1 (LRRTM1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRTM1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects LRRTM1 at C-term. LRRTM1 antibody is predicted to not cross-react with other LRRTM family members.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of human LRRTM1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for LRRTM1

Target: LRRTM1 (Leucine Rich Repeat Transmembrane Neuronal 1 (LRRTM1))

Alternative Name: LRRTM1 (LRRTM1 Products)

Synonyms: im:6904481 antibody, 4632401D06Rik antibody, AW125451 antibody, leucine rich repeat transmembrane neuronal 1 antibody, lrrtm1 antibody, LRRTM1 antibody, Lrrtm1 antibody

Background: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM1 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.Synonyms: Leucine-rich repeat transmembrane neuronal protein 1

Gene ID: 347730

NCBI Accession: NP_849161

UniProt: Q86UE6

Pathways: Synaptic Membrane