LRRTM4 antibody (Center)

Catalog No. ABIN783389

Product Details anti-LRRTM4 Antibody

Target: LRRTM4 (Leucine Rich Repeat Transmembrane Neuronal 4 (LRRTM4))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRTM4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects LRRTM4 at Center. At least two isoforms of LRRTM4 are known to exist, this antibody will both isoforms. LRRTM4 antibody is predicted to not cross-react with other LRRTM family members.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the center of human LRRTM4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Antibody is supplied in PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for LRRTM4

Target: LRRTM4 (Leucine Rich Repeat Transmembrane Neuronal 4 (LRRTM4))

Alternative Name: LRRTM4 (LRRTM4 Products)

Synonyms: 7530419J18Rik antibody, A230052N11 antibody, RGD1560707 antibody, DKFZp459D155 antibody, leucine rich repeat transmembrane neuronal 4 antibody, LRRTM4 antibody, Lrrtm4 antibody, lrrtm4 antibody

Background: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Little is known about the function of LRRTM4, in mouse, it is expressed in the limb mesenchyme, neural tube, caudal mesoderm and in three distinct regions of the head. Later expression occurs in a subset of the developing sclerotome. Its similarity to other LRRTM family members suggests that LRRTM4 may also play a role in the development and maintenance of the vertebrate nervous system.Synonyms: Leucine-rich repeat transmembrane neuronal protein 4

Gene ID: 80059

NCBI Accession: NP_001128217

UniProt: Q86VH4

Pathways: Synaptic Membrane