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Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) (N-Term) antibody

Details for Product No. ABIN783460
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Antigen
Synonyms EZH1, KMT6B, AW557915, mKIAA0388, si:ch211-250i3.1, zgc:136829, enx-1, enx1, ezh1, ezh2, kmt6, xez
Epitope
N-Term
(14), (9), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(56), (32), (22), (15), (13), (13), (12), (12), (1), (1), (1)
Host
Rabbit
(50), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(45), (26), (16), (10), (10), (3), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN783460
401.50 $
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Immunogen 18 amino acid peptide near the amino terminus of human EZH1
Specificity This antibody detects EZH1 at N-term. EZH1 antibody is predicted to not cross-react with EZH2. Species Reactivity: Tested: Human, mouse, rat
Purification Affinity chromatography purified via peptide column
Alternative Name EZH1
Background EZH1 was initially identified as a homolog of the drosophila Enhancer of Zeste through transcription mapping of chromosome 17q21. Both EZH1 and the related protein EZH2 can form complexes with the noncanonical Polycomb repressive complex-2 (PRC2) and maintain repressive chromatin, but the PRC2-EZH1 complex mediates methylation of histone H3. Both EZH1 and EZH2 are thought to function in the maintenance of embryonic stem cell pluripotency and plasticity and recently have been shown to be essential for hair follicle homeostasis and wound repair. Multiple isoforms of EZH1 are known to exist.
Alternate names: ENX-2, Enhancer of zeste homolog 1, Histone-lysine N-methyltransferase EZH1, KIAA0388
Gene ID 2145
NCBI Accession NP_001982
UniProt Q92800
Research Area Chromatin and Nuclear Signaling
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Abel, Brody, Valdes et al.: "Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1." in: Genomics, Vol. 37, Issue 2, pp. 161-71, 1997 (PubMed).

Validation Images
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