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Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) (N-Term) antibody

Details for Product No. ABIN783460, Supplier: Log in to see
Antigen
  • EZH1
  • KMT6B
  • AW557915
  • mKIAA0388
  • si:ch211-250i3.1
  • zgc:136829
  • enx-1
  • enx1
  • ezh1
  • ezh2
  • kmt6
  • xez
Epitope
N-Term
25
18
11
3
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
91
46
34
7
3
2
1
1
1
1
1
1
Host
Rabbit
78
15
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
75
48
34
13
11
10
3
1
1
1
1
1
Supplier
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Immunogen 18 amino acid peptide near the amino terminus of human EZH1
Specificity This antibody detects EZH1 at N-term. EZH1 antibody is predicted to not cross-react with EZH2.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Affinity chromatography purified via peptide column
Alternative Name EZH1 (EZH1 Antibody Abstract)
Background EZH1 was initially identified as a homolog of the drosophila Enhancer of Zeste through transcription mapping of chromosome 17q21. Both EZH1 and the related protein EZH2 can form complexes with the noncanonical Polycomb repressive complex-2 (PRC2) and maintain repressive chromatin, but the PRC2-EZH1 complex mediates methylation of histone H3. Both EZH1 and EZH2 are thought to function in the maintenance of embryonic stem cell pluripotency and plasticity and recently have been shown to be essential for hair follicle homeostasis and wound repair. Multiple isoforms of EZH1 are known to exist.Synonyms: ENX-2, Enhancer of zeste homolog 1, Histone-lysine N-methyltransferase EZH1, KIAA0388
Gene ID 2145
NCBI Accession NP_001982
UniProt Q92800
Research Area Chromatin and Nuclear Signaling
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) (N-Term) antibody (ABIN783460) Western blot analysis of EZH1 in mouse lung tissue lysate with EZH1 antibody at (A) 1...
Background publications Abel, Brody, Valdes et al.: "Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1." in: Genomics, Vol. 37, Issue 2, pp. 161-71, 1997 (PubMed).