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TCTN3 antibody (C-Term)

TCTN3 Reactivity: Human, Mouse, Rat WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783639
  • Target See all TCTN3 Antibodies
    TCTN3 (Tectonic Family Member 3 (TCTN3))
    Binding Specificity
    • 15
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 40
    • 19
    • 18
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 40
    Rabbit
    Clonality
    • 40
    Polyclonal
    Conjugate
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TCTN3 antibody is un-conjugated
    Application
    • 27
    • 13
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    17 amino acid peptide near the carboxy terminus of human TCTN3
    Top Product
    Discover our top product TCTN3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    TCTN3 (Tectonic Family Member 3 (TCTN3))
    Alternative Name
    Tectonic-3 (TCTN3 Products)
    Synonyms
    RGD1305166 antibody, C10orf61 antibody, JBTS18 antibody, OFD4 antibody, TECT3 antibody, 4930521E07Rik antibody, AI197391 antibody, Tect3 antibody, tectonic family member 3 antibody, Tctn3 antibody, TCTN3 antibody
    Background
    TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58 % similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.Synonyms: C10orf61, TCTN3, TECT3
    Gene ID
    26123
    NCBI Accession
    NP_056446
    UniProt
    Q6NUS6
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