SCUBE1 antibody (Center)
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- Target See all SCUBE1 Antibodies
- SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))
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Binding Specificity
- Center
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SCUBE1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 14 amino acid peptide near the center of human SCUBE1
- Top Product
- Discover our top product SCUBE1 Primary Antibody
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anti-Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1) (AA 453-566) antibody
SCUBE1 Reactivity: Human ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1) (AA 518-567) antibodySCUBE1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
anti-Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1) (C-Term) antibodySCUBE1 Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- 14 amino acid peptide near the center of human SCUBE1
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- Target
- SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))
- Alternative Name
- SCUBE1 (SCUBE1 Products)
- Synonyms
- 7330410C13Rik antibody, A630023E24Rik antibody, signal peptide, CUB domain and EGF like domain containing 1 antibody, signal peptide, CUB domain, EGF-like 1 antibody, SCUBE1 antibody, Scube1 antibody
- Background
- SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity, genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.Synonyms: Signal peptide CUB and EGF-like domain-containing protein 1
- Gene ID
- 80274
- NCBI Accession
- NP_766638
- UniProt
- Q8IWY4
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