CABP7 antibody (N-Term)

Catalog No. ABIN783667

Product Details anti-CABP7 Antibody

Target: CABP7 (Calcium Binding Protein 7 (CABP7))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CABP7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the amino terminus of human CaBP7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for CABP7

Target: CABP7 (Calcium Binding Protein 7 (CABP7))

Alternative Name: CABP7 (CABP7 Products)

Synonyms: CABP7 antibody, CALN2 antibody, rCaBP7 antibody, calcium binding protein 7 antibody, CABP7 antibody, Cabp7 antibody

Background: Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70 % homology with CaBP8 and 50 % homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.Synonyms: Calcium-binding protein 7

Gene ID: 164633

NCBI Accession: NP_872333

UniProt: Q86V35