Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

NLRC3 antibody (Center)

NLRC3 Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783697
  • Target See all NLRC3 Antibodies
    NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))
    Binding Specificity
    • 1
    • 1
    • 1
    Center
    Reactivity
    Human, Mouse, Rat
    Host
    • 3
    • 1
    Rabbit
    Clonality
    • 3
    • 1
    Polyclonal
    Conjugate
    • 4
    This NLRC3 antibody is un-conjugated
    Application
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects NOD3 at Center.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    18 amino acid peptide near the center of human NOD3
    Top Product
    Discover our top product NLRC3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))
    Alternative Name
    NOD3 (NLRC3 Products)
    Synonyms
    NLRC3 antibody, nod3 antibody, NLR-A3 antibody, NOD3 antibody, CLR16.2 antibody, D230007K08Rik antibody, mFLJ00348 antibody, Nlrc3-ps1 antibody, RGD1304902 antibody, NLR family CARD domain containing 3 antibody, NLR family, CARD domain containing 3 antibody, NLRC3 antibody, nlrc3 antibody, Nlrc3 antibody
    Background
    NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-?B, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.Synonyms: CLR16.2, FLJ00348, NLRC3, NOD3
    Gene ID
    197358
    NCBI Accession
    NP_849172
    UniProt
    Q7RTR2
You are here:
Support