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SLC39A3 antibody (Center)

SLC39A3 Reactivity: Human, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783799
  • Target See all SLC39A3 Antibodies
    SLC39A3 (Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 26
    • 12
    • 2
    Human, Mouse
    Host
    • 26
    • 1
    Rabbit
    Clonality
    • 27
    Polyclonal
    Conjugate
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC39A3 antibody is un-conjugated
    Application
    • 19
    • 15
    • 14
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects Zinc transporter ZIP3 / SLC39A3 at Center.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    16 amino acid peptide near the center of human ZIP3
    Top Product
    Discover our top product SLC39A3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    SLC39A3 (Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3))
    Alternative Name
    Zinc Transporter ZIP3 / SLC39A3 (SLC39A3 Products)
    Synonyms
    AI845814 antibody, Zip3 antibody, ZIP3 antibody, wu:fc84e09 antibody, zgc:158334 antibody, solute carrier family 39 (zinc transporter), member 3 antibody, solute carrier family 39 member 3 antibody, Slc39a3 antibody, slc39a3 antibody, SLC39A3 antibody
    Background
    The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.Synonyms: Solute carrier family 39 member 3, ZIP-3, ZIP3, Zrt- and Irt-like protein 3
    Gene ID
    29985
    NCBI Accession
    NP_653165
    UniProt
    Q9BRY0
    Pathways
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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