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Transmembrane Protein 18 (TMM18) (C-Term) antibody

TMM18 Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783829
  • Target See all Transmembrane Protein 18 (TMM18) Antibodies
    Transmembrane Protein 18 (TMM18)
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 32
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 32
    • 16
    • 13
    • 13
    • 13
    • 7
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to Transmembrane protein 18.
    Purification
    Affinity chromatography
    Immunogen
    15 amino acid peptide near the carboxy terminus of human TMEM18.
    Top Product
    Discover our top product TMM18 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    Transmembrane Protein 18 (TMM18)
    Alternative Name
    TMEM18 (TMM18 Products)
    Synonyms
    BC024093 antibody, transmembrane protein 18 antibody, transmembrane protein 18 L homeolog antibody, TMEM18 antibody, Tmem18 antibody, tmem18.L antibody
    Background
    Recent studies have examined how overexpression of certain genes enhances the tropism of neural stem cells (NSCs) for gliomas. Overexpression of Transmembrane protein 18 (TMEM18) provides NSCs and neural precursors an increased migration capacity towards glioblastoma cells in vitro and in the rat brain, while functional inactivation of the gene resulted in an almost complete loss of migration activity, suggesting that TMEM18 could be a potential target in NSC-based glioma therapy. Other recent results suggest that among others, the TMEM18 loci is associated with higher than normal body mass index (BMI) and obesity, indicating there may be a CNS-related role in predisposition to obesity. Multiple isoforms of TMEM18 are known to exist.Synonyms: Transmembrane protein 18
    Gene ID
    129787
    NCBI Accession
    NP_690047
    UniProt
    Q96B42
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