PPAPDC3 antibody (N-Term)

Catalog No. ABIN783832

Product Details anti-PPAPDC3 Antibody

Target: PPAPDC3 (Phosphatidic Acid Phosphatase Type 2 Domain Containing 3 (PPAPDC3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPAPDC3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography

Immunogen: 19 amino acid peptide from near the amino of terminus human PPAPDC3.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for PPAPDC3

Target: PPAPDC3 (Phosphatidic Acid Phosphatase Type 2 Domain Containing 3 (PPAPDC3))

Alternative Name: PPAPDC3 (PPAPDC3 Products)

Synonyms: MGC147268 antibody, im:7142624 antibody, zgc:77336 antibody, PPAPDC3 antibody, DKFZp468F176 antibody, C9orf67 antibody, NET39 antibody, D830019K17Rik antibody, RGD1305821 antibody, phospholipid phosphatase 7 (inactive) antibody, phospholipid phosphatase 7 antibody, plpp7 antibody, PLPP7 antibody, Plpp7 antibody

Background: PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.Synonyms: C9orf67, Phosphatidic acid phosphatase type 2 domain-containing protein 3, Probable lipid phosphate phosphatase PPAPDC3

Gene ID: 84814

NCBI Accession: NP_116117

UniProt: Q8NBV4

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development