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MMP11 antibody
MMP11
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MMP11 Antibody
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Target
See all MMP11 Antibodies
MMP11
(Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))
Reactivity
All reactivities for MMP11 antibodies
Human, Mouse, Rat
Host
All hosts for MMP11 antibodies
Rabbit
Clonality
All clonalities for MMP11 antibodies
Polyclonal
Conjugate
All conjugates for MMP11 antibodies
This MMP11 antibody is un-conjugated
Application
All applications for MMP11 antibodies
Western Blotting (WB)
Specificity
This antibody recognizes the latent form (~68 kDa) and the active forms (~55 kDa and ~40 kDa) of MMP-11.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Affinity chromatography
Immunogen
Synthetic peptide surrounding amino acid 464 of mouse MMP-11
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Discover our top product MMP11 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered saline (PBS) containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.
Target Details for MMP11
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Target
MMP11
(Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))
Alternative Name
MMP-11 (MMP11 Products )
Synonyms
SL-3 antibody, ST3 antibody, STMY3 antibody, Stmy3 antibody, MMP-11 antibody, matrix metallopeptidase 11 antibody, matrix metallopeptidase 11 L homeolog antibody, stromelysin-3 antibody, MMP11 antibody, Mmp11 antibody, mmp11.L antibody, LOC103694874 antibody
Background
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.Synonyms: MMP11, Matrix metalloproteinase-11, SL-3, ST3, STMY3, Stromelysin-3
Gene ID
4320
NCBI Accession
NP_005931
UniProt
P24347
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