DVL3 antibody

Catalog No. ABIN783856

Product Details anti-DVL3 Antibody

Target: DVL3 (Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DVL3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatographphy

Immunogen: Synthetic peptide surrounding amino acid 583 of mouse Dvl3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered saline (PBS) containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.

Target Details for DVL3

Target: DVL3 (Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3))

Alternative Name: Dishevelled-3 / DVL3 (DVL3 Products)

Synonyms: dsh3 antibody, dvl3 antibody, wu:fb75f04 antibody, wu:fi22h02 antibody, wu:fp61b09 antibody, dishevelled segment polarity protein 3 L homeolog antibody, dishevelled segment polarity protein 3 antibody, dishevelled segment polarity protein 3a antibody, dvl3.L antibody, dvl3 antibody, DVL3 antibody, Dvl3 antibody, dvl3a antibody

Background: Dvl1, Dvl2, and Dvl3 are mammalian homologs of Dsh (disheveled) proteins that are involved in Wnt signaling pathways. Upon treatment with Wnt proteins, Dvls become hyperphosphorylated and accumulate in the nucleus. Dvls have been reported to mediate endocytosis and may also play a role in certain cancers.Synonyms: DSH homolog 3, KIAA0208, Segment polarity protein dishevelled homolog DVL-3

Gene ID: 10090

UniProt: Q61062