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SMC2 antibody (C-Term)

SMC2 Reactivity: Human WB, EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN783969
  • Target See all SMC2 Antibodies
    SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))
    Binding Specificity
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 37
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Human
    Host
    • 33
    • 3
    • 1
    Goat
    Clonality
    • 33
    • 4
    Polyclonal
    Conjugate
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMC2 antibody is un-conjugated
    Application
    • 27
    • 12
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequence
    C-SKAKPPKGAH VEV Remarks: Reported variants NP_006435.2, NP_001036015.1 and NP_001036016.1 represent identical protein
    Specificity
    Recognizes SMC2/CAPE.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    Immunogen
    Peptide with sequence from the C Terminus of the protein sequence according to NP_006435.2. Genename: SMC2
    Top Product
    Discover our top product SMC2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))
    Alternative Name
    SMC2 / CAPE (SMC2 Products)
    Synonyms
    CAP-E antibody, CAPE antibody, SMC-2 antibody, SMC2L1 antibody, 5730502P04Rik antibody, AI255214 antibody, AW545314 antibody, Fin16 antibody, Smc2l1 antibody, fb92e05 antibody, wu:fb92e05 antibody, zeh1628 antibody, zgc:55326 antibody, xcap-e antibody, SCII antibody, structural maintenance of chromosomes 2 antibody, structural maintenance of chromosomes 2 L homeolog antibody, SMC2 antibody, Smc2 antibody, smc2 antibody, smc2.L antibody
    Background
    CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.Synonyms: CAP-E, Chromosome-associated protein E, SMC protein 2, SMC-2, SMC2L1, Structural maintenance of chromosomes protein 2, XCAP-E homolog
    Gene ID
    216
    NCBI Accession
    NP_006435
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