APOL1 antibody (Internal Region)

Catalog No. ABIN783973

Product Details anti-APOL1 Antibody

Target: APOL1 (Apolipoprotein L, 1 (APOL1))

Binding Specificity: AA 297-309, Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This APOL1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-PHASASRPRV TEP Remarks: Reported variants represent identical protein: NP_003652.2, NP_001130012.1

Specificity: This antibody is expected to recognize all three reported isoforms (NP_003652.2, NP_663318.1 and NP_001130013.1).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_003652.2, NP_663318.1, NP_001130013.1. Genename: APOL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for APOL1

Target: APOL1 (Apolipoprotein L, 1 (APOL1))

Alternative Name: Apolipoprotein L1 (Apo L1) (APOL1 Products)

Synonyms: APO-L antibody, APOL antibody, APOL-I antibody, FSGS4 antibody, wu:fa95b12 antibody, wu:fc30h04 antibody, si:rp71-1g18.12 antibody, apolipoprotein L1 antibody, apolipoprotein L, 1 antibody, APOL1 antibody, apol1 antibody

Background: Apolipoprotein L 1 is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. There are two isoforms.Synonyms: APOL1, ApoL-I, Apolipoprotein L-I

Gene ID: 216

NCBI Accession: NP_001130012