SNX18 antibody (C-Term)

Catalog No. ABIN784285

Product Details anti-SNX18 Antibody

Target: SNX18 (Sorting Nexin 18 (SNX18))

Binding Specificity: C-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This SNX18 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-KVQRVPLMTV LSF

Specificity: This antibody recognizes SNX18/SNAG1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_443102.2. Genename: SNX18

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SNX18

Target: SNX18 (Sorting Nexin 18 (SNX18))

Alternative Name: Sorting Nexin-18 (SNX18) (SNX18 Products)

Synonyms: snag1 antibody, MGC82637 antibody, SNX18 antibody, SNAG1 antibody, si:dkey-193c22.4 antibody, SH3PX2 antibody, SH3PXD3B antibody, Snag1 antibody, sorting nexin 18 L homeolog antibody, sorting nexin 18 antibody, sorting nexin 18 S homeolog antibody, sorting nexin 18a antibody, snx18.L antibody, SNX18 antibody, snx18.S antibody, snx18 antibody, snx18a antibody, Snx18 antibody

Background: May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.Synonyms: SH3 and PX domain-containing protein 3B, SH3PXD3B, SNAG1, Sorting nexin-associated Golgi protein 1

Gene ID: 112574

NCBI Accession: NP_443102