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Desmoglein 1 antibody
DSG1
Reactivity: Human
IHC (p), EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-Desmoglein 1 Antibody
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Target
See all Desmoglein 1 (DSG1) Antibodies
Desmoglein 1 (DSG1)
Reactivity
All reactivities for Desmoglein 1 antibodies
Human
Host
All hosts for Desmoglein 1 antibodies
Goat
Clonality
All clonalities for Desmoglein 1 antibodies
Polyclonal
Conjugate
All conjugates for Desmoglein 1 antibodies
This Desmoglein 1 antibody is un-conjugated
Application
All applications for Desmoglein 1 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to the internal region of DSG1.
Purification
Immunoaffinity chromatography
Immunogen
Synthetic peptide - KLH conjugated Remarks: Family: Cadherin Subfamily: not assigned-Cadherin
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0,5 mg/mL
Buffer
Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % sodium azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Desmoglein 1
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Target
Desmoglein 1 (DSG1)
Alternative Name
Desmoglein-1 (DSG1 Products )
Synonyms
CDHF4 antibody, DG1 antibody, DSG antibody, PPKS1 antibody, SPPK1 antibody, DSG-1 antibody, DSG1 antibody, Dsg1b antibody, Dsg1c antibody, desmoglein 1 antibody, desmoglein 4 antibody, DSG1 antibody, DSG4 antibody, Dsg1 antibody
Background
Desmosomes are a type of intercellular junction between epithelial, myocardial, and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein isoforms have been identified: DSG1, DSG2 and DSG3, all members of the cadherin cell adhesion molecule family. DSG1 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.Synonyms: CDHF4, Cadherin family member 4, DG1, DGI, DSG1, Desmosomal glycoprotein 1, Pemphigus foliaceus antigen
Gene ID
1828
NCBI Accession
NP_001933
Pathways
Cell-Cell Junction Organization
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