CD41, CD61 antibody (FITC)
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- Target See all CD41, CD61 Antibodies
- CD41, CD61 (CD41,CD61)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD41, CD61 antibody is conjugated to FITC
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Application
- Flow Cytometry (FACS)
- Purification
- Ion Exchange or Affinity Chromatography.
- Immunogen
- Human platelets. Hybridization of Sp2/0-Ag14 myeloma cells with spleen cells from Balb/c mice.
- Clone
- P2
- Isotype
- IgG1
- Top Product
- Discover our top product CD41, CD61 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS, pH 7.2 containing 2 mg/mL BSA as stabilizer and 0.09 % Sodium Azide as preservative.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- This product is photosensitive and should be protected from light
- Storage
- 4 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- Target
- CD41, CD61 (CD41,CD61)
- Abstract
- CD41, CD61 Products
- Background
- Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb
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