SETDB2 antibody (N-Term)

Catalog No. ABIN785415

Product Details anti-SETDB2 Antibody

Target: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETDB2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ASQKEVNAQS SDPMPVTQKE QENKSNAFPS TSCENSFPED CTFLTTGNKE

Predicted Reactivity: Guinea Pig: 92%, Human: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against SETDB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SETDB2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 707 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SETDB2

Target: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Alternative Name: SETDB2 (SETDB2 Products)

Synonyms: C13orf4 antibody, CLLD8 antibody, CLLL8 antibody, KMT1F antibody, Clld8 antibody, Gm293 antibody, SET domain bifurcated 2 antibody, SET domain, bifurcated 2 antibody, SETDB2 antibody, Setdb2 antibody

Background: Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity.
Alias Symbols: CLLD8, CLLL8, KMT1F, C13orf4
Protein Interaction Partner: ARL14EP, UBD, tat,
Protein Size: 707

Molecular Weight: 77 kDa

Gene ID: 83852

NCBI Accession: NM_001160308