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XRCC3 antibody (C-Term)

XRCC3 Reactivity: Human, Dog, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN786380
  • Target See all XRCC3 Antibodies
    XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
    Binding Specificity
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 42
    • 13
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Dog, Rabbit
    Host
    • 38
    • 6
    Rabbit
    Clonality
    • 39
    • 5
    Polyclonal
    Conjugate
    • 33
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This XRCC3 antibody is un-conjugated
    Application
    • 27
    • 15
    • 10
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LADRLREEEA ALGCPARTLR VLSAPHLPPS SCSYTISAEG VRGTPGTQSH
    Predicted Reactivity
    Dog: 92%, Human: 100%, Rabbit: 83%
    Characteristics
    This is a rabbit polyclonal antibody against XRCC3. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product XRCC3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 346 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
    Alternative Name
    XRCC3 (XRCC3 Products)
    Synonyms
    CMM6 antibody, 4432412E01Rik antibody, AI182522 antibody, AW537713 antibody, MGC69118 antibody, im:7142103 antibody, zgc:101608 antibody, si:dkey-11b8.1 antibody, xrcc3 antibody, XRCC3 antibody, X-ray repair cross complementing 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog antibody, XRCC3 antibody, Xrcc3 antibody, xrcc3.L antibody, xrcc3 antibody
    Background
    This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
    Alias Symbols: CMM6
    Protein Interaction Partner: SWSAP1, ZSWIM7, UBC, FANCG, BRCA2, ZNHIT3, RAD51D, RAD51C, RAD51,
    Protein Size: 346
    Molecular Weight
    38 kDa
    Gene ID
    7517
    NCBI Accession
    NM_005432, NP_005423
    UniProt
    O43542
    Pathways
    DNA Damage Repair
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