Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3) (C-Term), (AA 415-636) antibody

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Antigen
Synonyms KCND3, zgc:55306, wu:fi06g01, kv4.3, K(v)4.3, AW045978, Kncd3, Kv4.3, KCND3L, KCND3S, KSHIVB, KV4.3, kcnd3-A, xKv4.3
Epitope
AA 415-636, C-Term
(38), (35), (22), (17), (15), (4), (2), (2), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
(58), (44), (29), (21), (2), (2), (2), (1)
Host
Mouse
(40), (39)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
(78), (48), (36), (20), (18), (3), (2), (2), (1)
Pubmed 2 references available
Quantity 100 μg
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Immunogen Fusion protein amino acids 415-636 (cytoplasmic C-terminus) of rat Kv4.3
Clone S75-41
Specificity Detects ~75 kDa.
Sensitivity 1 µg/mL of SMC-377 was sufficient for detection of Kv4.3 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Purification Protein G Purified
Alternative Name Kv4.3 (KCND3 Antibody Abstract)
Background Potassium voltage-gated channel subfamily D member 3 (also knowns as Kv4.3) is a protein that in humans is encoded by the KCND3 gene. It contributes to the cardiac transient outward potassium current, the main contributing current to the repolarizing phase 1 of the cardiac action potential (1-3).
Cellular Localization: Cell Membrane (Sarcolemma)
Gene ID 65195
NCBI Accession NP_113927
UniProt Q62897
Research Area Cardiovascular, Ion Channels, Transporters
Application Notes Recommended Dilution: WB (1:1000), IHC (1:1000), ICC/IF (1:100)
Optimal dilutions for assays should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Supplier Images
anti-Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3) (C-Term), (AA 415-636) antibody Kv4 3 rat brain membranes 20ug Western Blotting 1 in 1000.
Background publications Gutman, Chandy, Grissmer et al.: "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels." in: Pharmacological reviews, Vol. 57, Issue 4, pp. 473-508, 2005 (PubMed).

Oudit, Kassiri, Sah et al.: "The molecular physiology of the cardiac transient outward potassium current (I(to)) in normal and diseased myocardium." in: Journal of molecular and cellular cardiology, Vol. 33, Issue 5, pp. 851-72, 2001 (PubMed).

Validation Images
Catalog No. ABIN863170
383.90 $
Plus shipping costs $45.00
Quantity
Price
100 μg
383.90 $

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