CRTC3 antibody

Catalog No. ABIN865461

Product Details anti-CRTC3 Antibody

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRTC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CRTC3 expressed in E. Coli.

Clone: 5G9

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, IHC: 1/200-1/1000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CRTC3

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Alternative Name: CRTC3 (CRTC3 Products)

Synonyms: torc3 antibody, MGC146372 antibody, 2610312F20Rik antibody, 6332415K15Rik antibody, AI429792 antibody, BC011210 antibody, TORC3 antibody, RGD1309666 antibody, TORC-3 antibody, CREB regulated transcription coactivator 3 antibody, CREB regulated transcription coactivator 3 L homeolog antibody, CRTC3 antibody, crtc3 antibody, Crtc3 antibody, crtc3.L antibody

Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) . Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach. Synonyms: TORC3, FLJ21868, CRTC3

Molecular Weight: 68kDa

Gene ID: 64784

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection