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Synapsin I (SYN1) (pSer549) antibody

Details for Product No. ABIN871415, Supplier: Login to see
Antigen
  • Synapsin-1
  • SYN1a
  • SYN1b
  • SYNI
  • Syn-1
  • si:dkey-90n12.3
  • SYN I
Epitope
pSer549
50
30
29
27
20
20
13
7
6
6
6
5
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus), Mouse (Murine)
240
192
172
44
11
10
6
4
4
2
2
1
Host
Rabbit
280
13
Clonality
Polyclonal
Conjugate
Un-conjugated
8
8
8
6
5
5
5
5
5
5
5
5
Application
Western Blotting (WB)
222
72
57
49
42
26
18
12
9
3
3
1
1
Supplier
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Immunogen Peptide sequence around phosphorylation site of pSer549 (P-A-S (p) -P-S) derived from Rat Synapsin Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
Specificity The antibody detects endogenous level of Synapsin only when phosphorylated at serine 549.
Purification Affinity purified
Alternative Name Synapsin (SYN1 Antibody Abstract)
Background Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level
Molecular Weight 78 kDa
Gene ID 20964
NCBI Accession NP_038708
UniProt O88935
Research Area Neurology
Pathways
Application Notes Western blotting: 1:500-1:1000
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Background publications Roskies: "The binding problem." in: Neuron, Vol. 24, Issue 1, pp. 7-9, 111-25, 2000 (PubMed).

Greengard: "Neuronal phosphoproteins. Mediators of signal transduction." in: Molecular neurobiology, Vol. 1, Issue 1-2, pp. 81-119, 1989 (PubMed).