MAGED1 antibody

Catalog No. ABIN871634

Product Details anti-MAGED1 Antibody

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGED1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: The antibody detects endogenous level of total Melanoma-associated antigen D1 protein.

Purification: Affinity purified

Immunogen: Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Application Details

Application Notes: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for MAGED1

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Alternative Name: Melanoma-associated antigen D1 (MAGED1 Products)

Synonyms: MAGED1 antibody, DLXIN-1 antibody, NRAGE antibody, 2810433C11Rik antibody, 5430405L04Rik antibody, DXBwg1492e antibody, Dlixin antibody, Dlxin-1 antibody, Dlxin1 antibody, MAGE-D1 antibody, mFLJ00163 antibody, Nrage antibody, MAGE family member D1 antibody, melanoma antigen family D, 1 antibody, melanoma antigen, family D, 1 antibody, MAGED1 antibody, Maged1 antibody

Background: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.

Molecular Weight: 95 kDa

Gene ID: 94275

NCBI Accession: NP_062765

UniProt: Q9QYH6

Pathways: Neurotrophin Signaling Pathway