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OCT4 antibody (POU Class 5 Homeobox 1) (AA 232-236)

Details for Product anti-POU5F1 Antibody No. ABIN871650, Supplier: Log in to see
Antigen
  • cb197
  • chunp6868
  • gp-9
  • gp9
  • NF-A3
  • Oct-3
  • Oct-3/4
  • Oct-4
  • Oct3
  • OCT3
  • Oct3/4
  • Oct4
  • oct4
  • OCT4
  • Otf-3
  • OTF-3
  • Otf-4
  • OTF3
  • Otf3
  • Otf3-rs7
  • Otf3g
  • OTF4
  • Otf4
  • POU-2
  • pou2
  • POU5F1
  • POU5F1L
  • spg/pou2
  • wu:fd18d06
Epitope
AA 232-236
50
32
31
21
20
13
12
8
7
6
5
5
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
342
137
60
15
12
11
10
10
5
5
5
3
3
3
2
1
1
Host
Rabbit
238
101
31
20
Clonality
Polyclonal
Conjugate
This OCT4 antibody is un-conjugated
14
12
11
10
6
6
6
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
296
163
68
54
54
42
40
19
16
11
8
4
3
3
3
2
2
1
Supplier
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Immunogen Peptide sequence around AA 232-236 (R-K-R-T-S) derived from OCT-4 Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Specificity The antibody detects endogenous level of total OCT-4 protein.
Purification Affinity purified
Alternative Name OCT-4 (POU5F1 Antibody Abstract)
Background Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency Pesce,
Molecular Weight 45 kDa
Gene ID 5460
NCBI Accession NP_002692
UniProt Q01860
Research Area Cancer
Application Notes Western blotting: 1:1000  
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Background publications Pan, Thomson: "Nanog and transcriptional networks in embryonic stem cell pluripotency." in: Cell research, Vol. 17, Issue 1, pp. 42-9, 2007 (PubMed).

Cauffman, Liebaers, Van Steirteghem, Van de Velde: "POU5F1 isoforms show different expression patterns in human embryonic stem cells and preimplantation embryos." in: Stem cells (Dayton, Ohio), Vol. 24, Issue 12, pp. 2685-91, 2006 (PubMed).

Bruserud, Gjertsen, Foss, Huang: "New strategies in the treatment of acute myelogenous leukemia (AML): in vitro culture of aml cells--the present use in experimental studies and the possible importance for future therapeutic approaches." in: Stem cells (Dayton, Ohio), Vol. 19, Issue 1, pp. 1-11, 2001 (PubMed).