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HSD17B10 antibody (AA 253-257)
HSD17B10
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HSD17B10 Antibody
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Target
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HSD17B10
(Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
Binding Specificity
All epitopes for HSD17B10 antibodies
AA 253-257
Reactivity
All reactivities for HSD17B10 antibodies
Human, Mouse, Rat
Host
All hosts for HSD17B10 antibodies
Rabbit
Clonality
All clonalities for HSD17B10 antibodies
Polyclonal
Conjugate
All conjugates for HSD17B10 antibodies
This HSD17B10 antibody is un-conjugated
Application
All applications for HSD17B10 antibodies
Western Blotting (WB)
Specificity
The antibody detects endogenous level of total ERAB protein.
Purification
Affinity purified
Immunogen
Peptide sequence around AA 253-257 (L-D-G-A-I) derived from Human ERAB. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Alternatives
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Application Details
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Application Notes
Western blotting: 1:500-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for HSD17B10
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Target
HSD17B10
(Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
Alternative Name
ERAB (HSD17B10 Products )
Synonyms
hadh2 antibody, im:6899159 antibody, wu:fj61f03 antibody, zgc:101605 antibody, abad antibody, camr antibody, erab antibody, hcd2 antibody, hsd10 antibody, mhbd antibody, mrpp2 antibody, mrx17 antibody, mrx31 antibody, mrxs10 antibody, schad antibody, sdr5c1 antibody, HADH2 antibody, HSD17B10 antibody, 17b-HSD10 antibody, ABAD antibody, CAMR antibody, DUPXp11.22 antibody, ERAB antibody, HCD2 antibody, MHBD antibody, MRPP2 antibody, MRX17 antibody, MRX31 antibody, MRXS10 antibody, SCHAD antibody, SDR5C1 antibody, 17bHSD10 antibody, Ads9 antibody, Hadh2 antibody, hydroxysteroid (17-beta) dehydrogenase 10 antibody, hydroxysteroid 17-beta dehydrogenase 10 antibody, hydroxysteroid (17-beta) dehydrogenase 10 L homeolog antibody, HSD17B10 antibody, hsd17b10 antibody, hsd17b10.L antibody, Hsd17b10 antibody
Background
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
Molecular Weight
27 kDa
Gene ID
3028
NCBI Accession
NP_004484
UniProt
Q99714
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